Allergic Disease - High Risk Infant

Pathway Contributor: Edmond Chan

Credentials:
MD, FRCPC

Bio:
Dr. Edmond S. Chan completed medical school and residency in pediatrics, and finished his training with a fellowship in pediatric clinical immunology and allergy. He is certified by the Royal College of Physicians and Surgeons in clinical immunology and allergy and practices in Vancouver. Currently, he is the head of the Division of Allergy & Immunology in the Department of Pediatrics. He is clinical associate professor at the University of British Columbia and program director of the UBC Pediatric Clinical Immunology and Allergy Fellowship training program. His other duties include: co-director, BC Children’s Hospital Eosinophilic Esophagitis Program, clinical investigator at the Child and Family Research Institute, pediatric section head of the Canadian Society of Allergy & Clinical Immunology, and clinical leader of the HealthLink BC Dietitian Allergy Advisory Council in the BC Ministry of Health Services. He is a fellow of the American Academy of Allergy, Asthma & Immunology. His research interests are in food allergy and eosinophilic esophagitis.

Contributions:

• What infant feeding formulas contribute to risk reduction for allergic diseases, including food allergy and eczema, among infants at high risk for allergy?  

  Role: Reviewer

• Do infants and children with a parental history of allergy who are exclusively breastfed and whose mothers avoid common allergenic foods during breastfeeding have a reduced incidence of allergy as compared to infants whose mothers do not restrict their diets?  

  Role: Reviewer

• Do infants with a parental history of allergy have a reduced incidence of allergy if their mothers avoid common allergenic foods during pregnancy as compared to infants of mothers who do not restrict their diets during pregnancy?  

  Role: Reviewer

• Does a history of maternal atopy predict a higher risk for the development of allergy in infants and children as compared to a paternal history of atopy?  

  Role: Reviewer

• Among infants with parental history of allergy, does a combination of maternal avoidance of common allergenic foods during breastfeeding, infant feeding with hydrolyzed formula, delayed introduction of common allergenic foods and a house dust mite reduction program decrease the incidence of allergy as compared to infant-mother pairs who do not adhere to these interventions?  

  Role: Reviewer

• Does the early introduction of common allergenic complementary foods in an infant’s diet decrease the risk of food allergy?  

  Role: Reviewer

• Among term infants and children with a parental history of allergy, does breastfeeding reduce the incidence of allergy?  

  Role: Reviewer

• Among healthy term infants, does early feeding of cow’s milk-based infant formula affect the risk of developing cow’s milk allergy?  

  Role: Reviewer

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