Disease Etiology
Irritable bowel syndrome (IBS) is a common gastrointestinal (GI) disorder of gut-brain interaction characterized by recurrent abdominal pain associated with altered bowel habit in the absence of organic disease (1,2). The pathophysiology of IBS is not completely understood. Symptoms are generated relating to features such as altered gut signaling (visceral hypersensitivity) and central nervous system dysregulation of the modulation of gut signaling and motor function,