Information in this section pertains to all global PEN® partners except where country flags are
								visible. Click on the flag(s) for country-specific information. If a country flag is not listed, there is
								no information specific to that country.
        
        
     
    
        Disease Etiology
Kidney Disease: Improving Global Outcomes (KDIGO) defines chronic kidney disease (CKD) as abnormalities of kidney function and structure that impact health and are present for >3 months (1). CKD differs from acute kidney injury (AKI), which is characterized by a sudden reduction in kidney function within 48 hours to seven days (2). Individuals with CKD may experience AKI (2). In 2020, KDIGO published new patient-centered nomenclature for kidney function and disease to enhance