Search Strategy

Content

What dietary and lifestyle strategies are recommended to treat pediatric dyslipidemia?

SEARCH TERMS

MeSH Terms

Pediatrics
Child
Dyslipidemias
Diet
Nutritional science

Text Words

Pediatric

Children

Dyslipidemia

DATABASES and Grey Literature Sources (e.g. international guidelines) Searched

PubMed

Trip

Epistemonikos

Canadian Cardiovascular Society

American Heart Association

European Society of Cardiology

Reasons for excluding reviews or studies identified using a hierarchical literature search

Barkas F, Nomikos T, Liberopoulos E, Panagiotakos D. Diet and Cardiovascular Disease Risk Among Individuals with Familial Hypercholesterolemia: Systematic Review and Meta-Analysis. Nutrients. 2020 Aug 13;12(8):2436. doi: 10.3390/nu12082436. PMID: 32823643; PMCID: PMC7468930. Abstract available from: https://pubmed.ncbi.nlm.nih.gov/32823643/

Majority of the studies involve adults (10 adult studies, 7sevenchild studies) and results were not analyzed according to age; therefore, cannot draw conclusion for the pediatric population.

Rosenson RS. Existing and emerging therapies for the treatment of familial hypercholesterolemia. J Lipid Res. 2021;62:100060. doi: 10.1016/j.jlr.2021.100060. Epub 2021 Mar 12. PMID: 33716107; PMCID: PMC8065289. Abstract available from: https://pubmed.ncbi.nlm.nih.gov/33716107/

Pharmacology review.

Roy G, Boucher A, Couture P, Drouin-Chartier JP. Impact of Diet on Plasma Lipids in Individuals with Heterozygous Familial Hypercholesterolemia: A Systematic Review of Randomized Controlled Nutritional Studies. Nutrients. 2021 Jan 15;13(1):235. doi: 10.3390/nu13010235. PMID: 33561083; PMCID: PMC7829745. Abstract available from: https://pubmed.ncbi.nlm.nih.gov/33561083/

Of the 19 RCTs, six involved children and results were not analyzed according to age.

Vuorio A, Kuoppala J, Kovanen PT, Humphries SE, Tonstad S, Wiegman A, Drogari E, Ramaswami U. Statins for children with familial hypercholesterolemia. Cochrane Database Syst Rev. 2019 Nov 7;2019(11):CD006401. doi: 10.1002/14651858.CD006401.pub5. PMID: 31696945; PMCID: PMC6836374. Abstract available from: https://pubmed.ncbi.nlm.nih.gov/31696945/

Pharmacology review.

Capra ME, Pederiva C, Viggiano C, De Santis R, Banderali G, Biasucci G. Nutritional Approach to Prevention and Treatment of Cardiovascular Disease in Childhood. Nutrients. 2021 Jul 10;13(7):2359. doi: 10.3390/nu13072359. PMID: 34371871; PMCID: PMC8308497. Abstract available from: https://pubmed.ncbi.nlm.nih.gov/34371871/

Good high level overview (not comprehensive/no added value).

DATE of Search

Date Search Completed: July 25, 2022

Search Limits (e.g. date, language): English language, Last 5 years